Blar i forfatter "Kamycheva, Elena"

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    • Bone mineral density is associated with Vitamin D related rs6013897 and estrogen receptor polymorphism rs4870044: The Tromsø study 

      Martinaityte, Ieva; Jorde, Rolf; Emaus, Nina; Eggen, Anne Elise; Joakimsen, Ragnar Martin; Kamycheva, Elena (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-02)
      Background:<br>Bone mineral density (BMD) is determined by bone remodeling processes regulated by endocrine, autocrine and genetic mechanisms. Thus, some studies have reported that BMD is associated with single nucleotide polymorphisms (SNPs) associated with vitamin D receptor (VDR), serum 25(OH)D levels and estrogen receptor 1 (ESR1), but without consensus. Therefore, we aimed to map and compare ...

    • Evaluation of Serum 25-Hydroxyvitamin D as a Predictor of Carotid Intima-Media Thickness and Carotid Total Plaque Area in Nonsmokers: The Tromso Study 

      Kamycheva, Elena; Johnsen, Stein Harald; Wilsgaard, Tom; Jorde, Rolf; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objective. Altered calcium homeostasis has been linked to increased intima-media thickness (IMT) and plaques. We aimed to investigate whether serum 25-hydroxyvitamin D (25(OH)D) and serum calcium are associated with IMT and plaques in nonsmoking population. Methods.Ultrasound of the right carotid arterywith themeasurements of IMT and plaqueswas performed in 4194 nonsmoking subjects with available ...

    • Genetic variations in the Vitamin D receptor predict type 2 diabetes and myocardial infarction in a community-based population: The tromsø study 

      Zostautiene, Leva; Jorde, Rolf; Schirmer, Henrik; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; Wilsgaard, Tom; Joakimsen, Ragnar Martin; Kamycheva, Elena (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-23)
      Background Though the associations between low serum 25-hydroxyvitamin D (25(OH)D) levels and health outcomes such as type 2 diabetes (T2D), myocardial infarction (MI), cancer, and mortality are well-studied, the effect of supplementation with vitamin D is uncertain. This may be related to genetic differences. Thus, rs7968585, a single nucleotide polymorphism (SNP) of the vitamin D receptor ...

    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) – a randomized controlled trial 

      Johansen, Jeanette Schultz; Halvorsen, Kjell H.; Svendsen, Kristian; Havnes, Kjerstin; Robinson, Eirin Guldsten; Wetting, Hilde Ljones; Haustreis, Stine; Småbrekke, Lars; Kamycheva, Elena; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      <b><p>Background</b> Suboptimal medication use contributes to a substantial proportion of hospitalizations and emergency department visits in older adults. We designed a clinical pharmacist intervention to optimize medication therapy in older hospitalized patients. Based on the integrated medicine management (IMM) model, the 5-step IMMENSE intervention comprise medication reconciliation, medication ...

    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial 

      Johansen, Jeanette Schultz; Havnes, Kjerstin; Halvorsen, Kjell H.; Haustreis, Stine-Mari; Skaue, Lillann Wilsgård; Kamycheva, Elena; Mathiesen, Liv; Viktil, Kirsten Kilvik; Granås, Anne Gerd; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-23)
      <p><i>Introduction:</i> Drug-related problems (DRPs) are common in the elderly, leading to suboptimal therapy, hospitalisations and increased mortality. The integrated medicines management (IMM) model is a multifactorial interdisciplinary methodology aiming to optimise individual medication therapy throughout the hospital stay. IMM has been shown to reduce readmissions and drug-related hospital ...

    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) – a randomized controlled trial 

      Johansen, Jeanette Schultz; Halvorsen, Kjell H.; Svendsen, Kristian; Havnes, Kjerstin; Robinson, Eirin Guldsten; Ljones Wetting, Hilde; Haustreis, Stine; Småbrekke, Lars; Kamycheva, Elena; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      Background - Suboptimal medication use contributes to a substantial proportion of hospitalizations and emergency department visits in older adults. We designed a clinical pharmacist intervention to optimize medication therapy in older hospitalized patients. Based on the integrated medicine management (IMM) model, the 5-step IMMENSE intervention comprise medication reconciliation, medication review, ...

    • Tracking of serum 25-hydroxyvitamin D during 21 years 

      Kubiak, Julia Magdalena; Kamycheva, Elena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-11)
      Background/objectives - Our objective was to evaluate the degree of tracking for serum levels of 25-hydroxyvitamin D [25(OH)D] over time, by using data from three previously conducted surveys of the Tromsø study collected in the years 1994/1995 (Tromsø 4), 2007/2008 (Tromsø 6), and 2015/2016 (Tromsø 7).<p> <p>Subjects/methods - Subjects with valid 25(OH)D measurements in all three surveys were ...

    • Vitamin D supplementation does not improve CVD risk factors in vitamin D-insufficient subjects 

      Kubiak, Julia Magdalena; Thorsby, Per Medbøe; Kamycheva, Elena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06)
      <p><i>Objective</i>: Low serum 25(OH)D levels are associated with cardiovascular disease (CVD) and some of its risk factors. However, in interventional studies, the effects of vitamin D supplementation have been uncertain, possibly due to inclusion of vitamin D-sufficient subjects. Our aim was therefore to examine effects of vitamin D supplementation on CVD risk factors in vitamin D-insufficient ...